Pathophysiology of Peripheral Nerve Injuries : A Brief Review

Abstract

Peripheral nerve injury can be disturbing for a patient.
The complicated dynamic degenerative processes are
influenced by several factors. This article reviews the
elemental mechanisms involved in a variety of nerve
injuries. It emphasizes some of the important aspects
of the complicated processes that underlie the
pathophysiology of nerve injury. This review will help
clinicians managing patients with peripheral nerve
injuries possess a clear understanding of the peripheral
nervous system’s response to trauma and various
pathogenetic processes in the background. It is
envisaged that a better understanding of the
degenerative and regenerative processes involved will
one day assist in the development of new therapies to
treat central nervous injury.